재료화학 연구실

For the design and synthesis of new nanoparticles, we consider various variables and precisely control them to discover new nanomaterials with desired properties and explore their emergent properties. Design of advanced synthetic process (Hot-injection, heating up, ligand-assisted reprecipitation etc.) Magnetic resonance imaging (MRI) has become one of the important methods of clinical disease diagnosis, and 40%~50% of clinical MRI examinations require the use of contrast agents to improve the sensitivity of MRI. Therefore, MRI contrast agents have also become important clinical diagnostic drugs. Superparamagnetic iron oxide nanoparticles (IONP) are frequently used as T2 contrast agent in vivo since the high safety and good biocompatibility. To improve the sensitivity and the MR contrast effects, we are focusing on the development of chemically engineering (multifunctional surface ligand synthesis and ligand exchange) and controlled assembly, which can provide a unique approach to manipulate the collective magnetic properties of the IONP that directly influence their MR contrast effects.