곽민석 연구실

It is my pleasure to welcome you to IBS Center for NanoMedicine at Yonsei University. IBS Center for NanoMedicine aims to bring people from different scientific backgrounds from all over the world to develop the future of interdisciplinary science. Our goal is to revolutionize the science of future medicine: developing nanomaterials and devices capable of monitoring and understanding biological phenomena with maximum precision and accuracy. In the long term, we expect to have innovative concepts and tools for ultra-sensitive, high-accuracy, and high-efficiency diagnosis and treatment of diseases for betterment of humankind in the future. To accomplish this goal, we provide all our members including graduate students with access to world-class state-of-the-art labs and interactive open spaces. We also run a graduate program of Nano Biomedical Engineering (Nano BME) to foster young science leaders for the next generation. It is our vision and hope to serve the society and global community we live today, and make our center as a successful showcase for the future interdisciplinary science. Machines found in nature and human-made machines share common components, such as an engine, and an output element, such as a rotor, linked by a clutch. This clutch, as seen in biological structures such as dynein, myosin or bacterial flagellar motors, allows for temporary disengagement of the moving parts from the running engine. However, such sophistication is still challenging to achieve in artificial nanomachines. Here we present a spherical rotary nanomotor with a reversible clutch system based on precise molecular recognition of built-in DNA strands. The clutch couples and decouples the engine from the machine"s rotor in response to encoded inputs such as DNA or RNA. The nanomotor