줄기세포및생체재료공학 연구실 (Stem Cell and Biomaterial Engineering Lab)

We synthesize novel biocompatible and virus-free nanoparticles that can improve the efficiency of gene transfer for gene therapy and cellular reprogramming. We engineer both natural and synthetic polymers, as well as cell-derived molecules, to develop safe and efficient nanoparticle-based gene and drug delivery systems. One key focus of our research is the development of lipid nanoparticles and nanovesicles as delivery carriers for DNA, mRNA, and siRNA delivery systems. These nanoparticles can efficiently deliver their cargo to target cells and tissues while minimizing off-target effects. Another area of focus is the development of adhesive hydrogel-based topical drug delivery systems to treat various diseases, such as wounds, ischemia, muscle, and bone defects. These systems can provide sustained and controlled release of therapeutic agents, which can improve the therapeutic outcomes while minimizing side effects. Stem Cell and Biomaterial Engineering Lab (SCBEL) develops advanced biomedical platforms for tissue engineering and regenerative medicine to improve human health.