안현서 연구실

Our research spans across all fields of renewable energy science, particularly those involving electrochemically induced chemical transformation. Reactive oxygen species (ROS) and reactive nitrogen species (RNS), which are key metabolic molecules involved in cellular respiration and intercellular signaling, play significant roles in gene expression, apoptosis, and the mechanisms of various diseases. Our laboratory conducts research utilizing scanning electrochemical microscopy (SECM) to precisely measure ROS and RNS at the single-cell level. SECM is a non-invasive, high-resolution electrochemical imaging tool capable of observing chemical changes in the intracellular and extracellular microenvironment in real time, providing powerful insights into cellular processes. Using a platinized carbon nanoelectrode fabricated through laser puller and Pt black deposition, we can measure the generation of reactive species within cells without causing any damage to the cells. Electrochemical sensors have the advantages of high selectivity, portability, and low energy consumption. We aim to develop a system that utilizes electrochemical sensors to detect compounds among the VOCs exhaled by humans, which can serve as biomarkers for diseases. This system will enable the proactive and non-invasive diagnosis of various diseases.