나노전자소자 및 센서 연구실

Electrochemical sensors are molecular sensing devices that intimately couple a biological recognition element to an electrode transducer. Such devices produce an accurate, sensitive, simple, inexpensive, compact, and low-power platform for point-of-care diagnosis. The most common example is a glucose sensor, in this system glucose oxidase is immobilized in the working electrode of an electrochemical cell (3 electrode system) and the current from the oxidation-reduction reaction is detected through cyclic voltammetry, differential pulse voltammetry, amperometry, and various other electrical methods. Our lab focuses on electrochemical measurements for the multiple detections of different biomarkers for specific diagnoses, such as Sepsis. Also, a study focused on Recombinase Polymerase Amplification (RPA) assay, an isothermal DNA amplification technology, combined with electrochemical techniques to investigate the presence of viruses in the human samples was developed before. Currently, we are working in collaboration with other research groups to develop a diagnostic device for a new Parkinson's disease biomarker. With different substrates, electrodes, nanomaterials, and fabrication techniques, we can optimize the sensitivity and selectivity of the sensing platforms. (a) Flexible and Printed PET-based sensor (WE/CE: Ti/Au and RE: Ag) with an active layer surface composed of the nanocomposite and the immobilized bioreceptor. (b) The variation of the peak currents with the DPV responses (inset graphs) for various concentrations of PCT in the human plasma.