대사 및 유전 질환 연구실

We study how cilia are formed, maintained, and regulated, and how mutations in cilia-related genes lead to rare genetic diseases. Each research card links to a detail page with specific goals and methods. We study how cellular signaling and organelle-level defects influence adipose tissue biology, energy expenditure, and whole-body metabolic homeostasis. We study how aging interacts with metabolic stress, inflammation, and tissue damage to promote liver fibrosis and metabolic disease progression. The MNG Lab (Metabolic and Genetic disorders Lab) studies how cells maintain biological balance and how disruption of this balance leads to rare genetic diseases, obesity, metabolic disorders, and age-related disease progression. By combining molecular biology, cell biology, genetics, disease models, and translational approaches, we aim to uncover how organelle dysfunction, genetic defects, metabolic pathways, and aging-related processes contribute to human disease. Authors: Hwangbo K., Park J., Rho H., Woo D.C., Sung Y.H., Kim S.H., Song J., and Ko H.W. Authors: Kim S., Han H.J., Rho H., Kang S., Mukherjee S., Kim J., Kim D., Ko H.W., Lim S.M., Im S.S., Chung J.Y., and Song J. Authors: Choi H.S., Park H., Min H., Kim K.S., Kim S.M., Li J., Liu C., Ko H.W., Lee M.G., Song L., Zhao B., and Bok J.