Laboratory of Catalysis & Stereoselective Chemical Synthesis

Our research is dedicated to the design, discovery, and development of innovative catalytic platforms for (stereo)selective organic and organometallic transformations. We are equally committed to advancing the fundamental understanding of catalytic processes, which we believe is essential for meaningful innovation in chemical synthesis. We develop catalytic systems that enable new modes of reactivity in organic and organometallic chemistry. Particular emphasis is placed on designing catalysts that promote structural and stereochemical diversity, thereby expanding the accessible chemical space. We aim to discover novel reactions and refine them into efficient, practical, and scalable synthetic methods. These transformations often address long-standing challenges in selectivity, functional group compatibility, and synthetic utility. A deep mechanistic understanding guides our catalyst design and optimization efforts. We investigate the fundamental reactivity of catalysts and key intermediates using a combination of experimental and theoretical tools. This mechanistically driven approach allows us to enhance the rate, yield, selectivity, and scope of catalytic processes. Our specific research directions are organized around the chiral catalytic systems that form the foundation of our work in (asymmetric) synthesis. Program 1 focuses on establishing chiral multi-catalytic systems, while Programs 2 and 3 emphasize the design of catalyst molecular structures. Each program aims to explore and expand the capabilities of catalytic platforms for enabling new chemical transformations.